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Quality Seeds Since 1896

Page Seed Office – 1918

Quality Seeds Since 1896

Germination Testing Room – 1930s

The Page Seed Company, Inc

American owned and operated, The Page Seed Company has provided quality products to the gardening community since 1896. Both professional horticulturalists and hobby gardeners rely on our abundant selection of Flowers, Vegetables, Herbs and Organic Varieties. Page’s takes great pride in our seed selection and purchases. Our company strictly works with suppliers having the best quality and highest germination available in the market. We do not offer any retail or custom imprinted packets that are “Genetically Engineered”.

As one of the largest seed companies in the world, we offer multiple brands targeted to specific retail markets, wholesale packaging and distribution for branded programs, custom imprinted products for business’ promotional needs, and community based educational programs. At Page’s Seeds, from planting the first seed all the way to harvest, we are dedicated to helping our customers grow. Thank you for your trust!

Our Products

Today’s gardening customer expects three things from their garden seed purchases: they want to know that they can trust in the product and the company, that they’re getting a good value, and that whatever they purchase…will grow. For over 100 years, Page Seed has supplied the highest quality products, rigorously tested to ensure germination levels at the best consumer value in the industry.

American owned & operated, The Page Seed Company, Inc. has provided quality products to professional horticulturalists & hobby gardeners since 1896. As one of the largest seed companies in the world, we offer multiple brands for retail markets, wholesale packaging and distribution for branded programs, custom imprinted products for business' promotional needs and community based educational programs.

Central nervous system activity of acute administration of ethanol extract of Punica granatum L. seeds in mice

Affiliation

  • 1 Department of Pharmacy, MJP Rohilkhand University, Bareilly, 243 006 India. [email protected]
  • PMID: 19245177

Central nervous system activity of acute administration of ethanol extract of Punica granatum L. seeds in mice

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Authors

Affiliation

  • 1 Department of Pharmacy, MJP Rohilkhand University, Bareilly, 243 006 India. [email protected]
  • PMID: 19245177

Abstract

Role of ethanolic extract of P. granatum seeds on central nervous system (CNS) in animal models of elevated plus maze test, barbiturate-induced sleeping time, tail suspension test, hot-plate and tail-flick test was studied. P. granatum (PG) extract was administered to young and aged mice at single doses of 100, 250 and 500 mg/kg, perorally while diazepam (1 mg/kg), morphine (5 mg/kg) and imipramine (30 mg/kg) were used intraperitoneally as standard drugs. The results showed that PG extract at all dose levels significantly exhibited the anxiolytic activity. In another study PG extract (250 and 500 mg/kg) significantly increased the sleeping latency and reduced the sleeping time. Tail suspension test showed that PG extract (250 and 500 mg/kg) was able to induce a significant decrease in the immobility time, similar to imipramine, a recognized antidepressant drug. Tail-flick and hot-plate tests exhibited antinociceptive property of PG extract, similar to morphine, a recognized antinociceptive agent. Phytochemical investigation of ethanol extract for the presence of phenolic compounds, flavonoids, tannins, anthocyanins, sugars and saponins was also carried out. Phytochemical screening and measurement of reducing power revealed the CNS activity of ethanol extract of PG seeds may be due to its antioxidative profile.

Role of ethanolic extract of P. granatum seeds on central nervous system (CNS) in animal models of elevated plus maze test, barbiturate-induced sleeping time, tail suspension test, hot-plate and tail-flick test was studied. P. granatum (PG) extract was administered to young and aged mice at single d … ]]>