marijuana and valium

Cannabis vs Diazepam: data & facts

by Viola Brugnatelli · Published May 5, 2015 · Updated November 21, 2017

Cannabis vs Diazepam (Valium)

As a scientist, I firmly believe in the power of data and facts.

That is why I wanted the facts I am presenting here to speak for themselves.

Diazepam (Valium) is a member of the Benzodiazepine family of drugs. It is prescribed for treating anxiety, pain, seizures and muscle spasms.

Paradoxically, amongst its frequent side effects, there are agitation and anxiety, muscle spasticity and tremor along with a long list of many other.

Yet, at contrary of Cannabis and its many therapeutical uses, Diazepam is one of the most prescribed medications, both in infants and elderly.

According to USA government estimates, doctors issue about 15 million Diazepam prescriptions annually in the United States only.

Abuse of benzodiazepines is very common, especially for the highly addictive properties of the drug.

The number of people admitted to treatment programs for abusing this drug increased nearly 570 percent from 2000 to 2010. (1)

Comparison of therapeutic properties: Cannabis vs Diazepam

Disease target Cannabis Diazepam
Diseases of Energy Metabolism Appetite regulation
Pain and Inflammation Acute pain (chemical, mechanical, thermal)
Chronic pain (inflammatory, neuropathic)
Central Nervous System Disorders Alzheimer’s Disease
Epilepsy Epilepsy
Insomnia Insomnia
Multiple Sclerosis
Nausea and emesis
Neurotoxicity and neurotrauma
Spinal Cord Injury
Amyotrophic Lateral Sclerosis
Movement Disorders (Basal Ganglia Disorders) Dystonia
Gilles de la Tourette’s syndrome
Huntington’s disease
Muscle spasms Muscle spasms
Parkinson’s disease and levodopa-induced dyskinesia
Tardive dyskinesia
Mental Disorders Anxiety Anxiety
Delirium tremens
Cardiovascular and Respiratory Disorders Asthma
Circulatory Shock
Myocardial Reperfusion Injury
Cancer Antiprolific
Eye Disorders Glaucoma
Gastrointestinal and Liver Disorders Hepatitis
Inflammatory Bowel Disease
Liver cirrhosis
Musculoskeletal Disorders Arthritis

Comparison of side effects: Cannabis vs Diazepam

As you scroll along the list, you will notice that in order to match the two colomns with corresponding “in target” effects, the effects on the left-side colomn (Cannabis) are often beneficial.

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Viola Brugnatelli is a Neuroscientist specialised in Cannabinoid circuitry & GPCRs signalling. Her academy and research training let her gain extensive experience on medical cannabis and terpenes both from preclinical as well as clinical perspective. In her vision, collective human knowledge behold the power for overall improvement of life, thus, it should be accessible and shareable. Viola is Founder of the science online magazine Nature Going Smart, and works as a consultant for companies & individual patients, as a speaker at seminars and workshops and as a lecturer in a CME course on Medical Cannabis in Italy, at the University of Padua.

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8 Responses

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Very interested. I have epilepsy, depression, insomnia , muscle spasms , and PTSD .

Dear Victoria,
we are sorry to hear this. We have quiet a lot of material that cover these topics if you like to check out:

We hope you will feel better soon.
If you have any enquiry please don’t hesitate to contact us, we do offer a consulting service as well.

I have COPD any help for that using Cannabis?

Cannabis is a great anti-inflammatory & bronchodilator, it would definitely aid the inflamed lining of airways to distend & decrease the overproduction of mucus, thus making it easier to breathe. It would help you if you have chronic bronchitis, however, make sure to never intake cannabis by smoking, as it may worsen your symptoms. You can check our guides on vaporizers & tea.
All best!

This is a load of crap. The side effects listed are rare, which you forgot to mention. A shame you didn’t list the effects that diazepam usually has on people (such as a decrease in anxiety, treatment for insomnia, etc.). . Reading this list you would think that diazepam causes restlessness and anxiety in everyone( among other things), which is the complete opposite of what it actually does. I won’t deny that the potential for abuse is probably pretty high, but marijuana is actually abused much more frequently. I have a kid that uses it, and he has turned into a lazy slob since he started using it. He no longer has any motivation, which is a side effect that was left out.

Hi Stacie, thanks for sharing your views. Very important points you are making. I am sorry to hear you feel this article isn’t representing the reality you are experiencing. It is true that some people have the impression that cannabis impairs motivation in chronic users. For this reason scientists at USC have carried out a large study on 487 individuals who consume daily cannabis and from their results: “Robust statistical methods controlling for heteroscedasticity, non-normality and extreme values found no differences in motivation but a small difference in subjective wellbeing. Medical users of cannabis reporting health problems tended to account for a significant portion of subjective wellbeing differences, suggesting that illness decreased wellbeing.Thus, daily use of cannabis does not impair motivation.”
So it seems that rather then being the trigger to a lack of motivation, cannabis might be used (or abused) when in lack of motivation, to hinder a stressed or simply bored state.
I Hope this information will support an informed & loving conversation with your son.

I have asthma, fybromyalgia, polymiositis, cervical spondylosis, osteoarthritis. rheumatoid arthritis, osteoporosis, carpel tunnel, an underactive thyroid (post surgery after graves disease), am bipolar as well as having anxiety and depression, I am a high function autistic … I take a number of meds to manage my illnesses which over time have been minimised as much as I can to the very basic pharma medications, which includes (recently) gastro meds for silent gastric reflux disease. I also take vitamins and mineral supplements (garlic, selenium, brewers yeast, vit c and vit c with zinc, ginge) in my efforts to minimise pharma meds which were making me more ill than my illnesses. I really want to try cbd oil but don’t know how to go about this and whether or not to try drops under the tongue or vaping. How would I go about trying the use of cbd alongside the above meds?

Thank you for entrusting in us. Medical cannabis has indeed greatly benefited patients suffering from many of the conditions that you mention; However, as for dosages, administration forms and possible interactions with current meds, you need to discuss this with your physician who will prescribe your tailored therapy. I hope this helps, best of luck!

As a scientist, I firmly believe in the power of data & facts. That's why I wanted the facts I am presenting to speak for themselves: Cannabis vs Diazepam

Drug Interactions between cannabis and Valium

This report displays the potential drug interactions for the following 2 drugs:

  • cannabis
  • Valium (diazepam)

Interactions between your drugs

diazePAM cannabis (Schedule I substance)

Applies to: Valium (diazepam) and cannabis

Using diazePAM together with cannabis (Schedule I substance) may increase side effects such as dizziness, drowsiness, confusion, and difficulty concentrating. Some people, especially the elderly, may also experience impairment in thinking, judgment, and motor coordination. You should avoid or limit the use of alcohol while being treated with these medications. Also avoid activities requiring mental alertness such as driving or operating hazardous machinery until you know how the medications affect you. Talk to your doctor if you have any questions or concerns. It is important to tell your doctor about all other medications you use, including vitamins and herbs. Do not stop using any medications without first talking to your doctor.

Drug and food interactions

diazePAM food

Applies to: Valium (diazepam)

Grapefruit and grapefruit juice may interact with diazePAM and lead to potentially dangerous side effects. Discuss the use of grapefruit products with your doctor. Do not increase or decrease the amount of grapefruit products in your diet without first talking to your doctor. Do not drink alcohol while taking diazePAM. This medication can increase the effects of alcohol. You may feel more drowsy, dizzy, or tired if you take diazePAM with alcohol. Talk to your doctor or pharmacist if you have any questions or concerns.

cannabis (Schedule I substance) food

Applies to: cannabis

Alcohol can increase the nervous system side effects of cannabis (Schedule I substance) such as dizziness, drowsiness, and difficulty concentrating. Some people may also experience impairment in thinking and judgment. You should avoid or limit the use of alcohol while being treated with cannabis (Schedule I substance). Do not use more than the recommended dose of cannabis (Schedule I substance), and avoid activities requiring mental alertness such as driving or operating hazardous machinery until you know how the medication affects you. Talk to your doctor or pharmacist if you have any questions or concerns.

Therapeutic duplication warnings

No warnings were found for your selected drugs.

Therapeutic duplication warnings are only returned when drugs within the same group exceed the recommended therapeutic duplication maximum.

See Also

  • Cannabis Drug Interactions
  • Valium Drug Interactions
  • Valium General Consumer Information
  • Drug Interactions Checker
Drug Interaction Classification
These classifications are only a guideline. The relevance of a particular drug interaction to a specific individual is difficult to determine. Always consult your healthcare provider before starting or stopping any medication.

Major Highly clinically significant. Avoid combinations; the risk of the interaction outweighs the benefit.
Moderate Moderately clinically significant. Usually avoid combinations; use it only under special circumstances.
Minor Minimally clinically significant. Minimize risk; assess risk and consider an alternative drug, take steps to circumvent the interaction risk and/or institute a monitoring plan.
Unknown No interaction information available.

Further information

Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.

Some mixtures of medications can lead to serious and even fatal consequences.

A Moderate Drug Interaction exists between cannabis and Valium. View detailed information regarding this drug interaction.