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Is It Safe to Mix LSD and Alcohol?

Mixing LSD — or any other drug for that matter — with alcohol is never recommended. That said, LSD and alcohol aren’t necessarily a life-threatening combo as long as you steer clear of heavy doses of either.

Healthline does not endorse the use of any illegal substances, and we recognize abstaining from them is always the safest approach. However, we believe in providing accessible and accurate information to reduce the harm that can occur when using.

When you combine LSD and alcohol, it reduces the effects of both substances. This may sound like a good thing if you’re looking to chill out or come down from an especially bad trip, but it’s not that simple.

When you aren’t feeling the effects of either substance as strongly, you’re more likely to reach for more, which can increase your risk of overdoing it with either substance.

Folks who’ve tried this combo report a bit of an unpredictable experience. Some people find it makes for a happier, more uplifting trip. Others, though, report having very strange trips or just vomiting like crazy.

As with any substance, how you’ll react depends on factors like:

  • how much of each you ingest
  • whether or not you’ve eaten
  • your body size and composition
  • any other medications you may be taking
  • preexisting physical and mental health conditions
  • tolerance to either LSD or alcohol
  • your surroundings

All substances come with risks — and LSD and alcohol are no different.

Mixing LSD with alcohol lowers the perceived effects of alcohol, which increases your risk of drinking too much. This can make you more vulnerable to the usual risks of alcohol, including alcohol poisoning or a nasty hangover.

Speaking of hangovers, mixing LSD and alcohol increases the potential for a rough comedown that can include nausea and vomiting, according to people who’ve been there, done that, and shared it online.

There’s also always the possibility of having a bad trip when you take LSD. Adding alcohol into the equation can make a bad trip worse and potentially make you aggressive, hostile, or even violent.

Before using any substance, it’s important to consider how it might interact with other substances you use or medications you take.

Other recreational substances

Not every substance has been studied for potential interaction with LSD, so it’s impossible to predict the outcome of combining LSD with other substances you may be taking.

We do know, however, that mixing any of the following substances with LSD can result in increased effects of both substances:

  • DMT
  • DXM
  • ketamine
  • MDMA
  • mushrooms

Mixing LSD with cocaine or cannabis can cause overstimulation and physical discomfort, depending on how much you use. Generally, the more you use of either substances with LSD, the more discomfort you’ll experience.

Prescription medication

LSD can also lessen the effect of certain medications, preventing them from working properly.

Some of these drugs include:

Again, it’s generally best to avoid mixing alcohol with other substances. Interactions can be unpredictable and are never exactly the same for two people.

If you’re still planning to combine the two, there are some precautions you can take to make the process a bit safer.

  • Having a trip-sitter. A trip-sitter is someone who stays with you and looks after you during a trip. Your cat doesn’t count. They should be someone you trust and who will stay sober the entire time in case you need help. Ideally, it should be someone who has experience with psychedelics and can spot the signs of a bad trip in the making or signs of an overdose.
  • Doing it somewhere safe. You should always be in a safe and comfortable place when tripping.
  • Limiting your alcohol intake. Since the risk of drinking too much is higher when you mix LSD and booze, you’ll want to find a way to limit your drinks. Keep just a small amount of alcohol with you, or go somewhere with limited access to alcohol. Also, tell your trip-sitter to stop you at a certain number of drinks.
  • Minding your dosing. Taking the right dose is key when using acid. Taking too much increases the risk of negative effects whether you’re drinking or not. Give the LSD time to kick in before adding alcohol to the mix or redosing.
  • Staying hydrated. Sipping water can help you stay hydrated. Too much alcohol can cause dehydration and psychedelic drugs increase body temperature, which can also be dehydrating. Water can help you pace your drinking and help reduce hangover and comedown symptoms. Having a few crackers on hand to help settle your stomach and slow the absorption of alcohol into your bloodstream is a good idea, too.
  • Considering your mood. Your chances of a bad trip are a lot higher if you take LSD while your head’s in a negative space. Also, alcohol is a depressant, so combining the two when you’re already feeling down will just further bring you down.

When to get help

If you or someone experiences any of the following while using LSD, alcohol, or other substances, call 911 right away:

  • irregular or shallow breathing
  • irregular heart rate
  • confusion
  • convulsions
  • hallucinations or delusions
  • seizure
  • loss of consciousness

If you’re concerned about law enforcement getting involved, you don’t need to mention the substances used over the phone. Just be sure to tell them about specific symptoms so they can send the appropriate response.

If you’re caring for someone else, get them to lay slightly on their side while you wait. Have them bend their top knee inward if they can for added support. This position will keep their airways open in case they begin to vomit.

Mixing LSD and alcohol can result in a not-so-pleasant trip and comedown.

5 things not to do on acid

Kai M
Jul 24, 2019 · 4 min read

People without experience of psychedelics such as acid/LSD are in the unfortunate position of being prone to treat them just like any other drug. They are likely to be reckless with how and when they take it. While being reckless might not be so important with other substances, I find that LSD requires at least a little preparation or knowledge before taking it if you want to have a great time.

With that in mind, here are f i ve things you should not do on acid. Most of these (other than #3) are essentially just my opinion and perhaps only apply to beginners and newcomers to the drug.

This list also only applies to those embarking on a full-blown trip (70ug+), not those taking microdoses (1–15ug).

Get angry

Out of the vast spectrum of emotions capable of being experienced, I believe anger to be the hardest to control when in a psychedelic headspace. LSD subjects you to thought loops, and if you get stuck in a loop when angry then you’ll find it unimaginably easy to indulge in self-destructive behaviour. Unlike mere sadness, anger energizes you; it’s a type of energy which you really don’t need when on a drug as stimulating as acid.

Angry trips are strange. Emotions change the way you react to the visuals, and anger can heavily warp your relationship with them.

One thing you’ll certainly not want to do is engage in an argument with someone (especially someone close to you) while on acid because you’ll end up spending the rest of the week thinking about it from every possible angle.

Go to a rave

Acid can be a fun drug, but it is not a party drug in the conventional sense. Taking it can make you surprisingly fragile mentally, and fragility is not what you want when you’re in such a crowded and energetic place as a rave.

Raves overflow the senses with both intense sound and light. While on some drugs this can actually enhance an experience, on acid it can make things a little too confusing. LSD is a magnifying glass, it will intensify anything that you focus on. So when you focus on something that is already loud or bright, it will make it feel all the much louder and brighter.

Additionally, raves have a tendency to be dirty, and one of the number one rules when preparing for an LSD trip is to make sure that your immediate surroundings are clean and tidy. Messy areas can throw people off, especially around the peak.

Drive

This one’s self-explanatory, but I’ll spell it out anyway. The psychedelic headspace is far too detached from sober living to be operating machinery of any sort. The reason I include it in this list is because being high on LSD is so different from being high on weed or being drunk. Sometimes LSD can make you feel deceptively clear-headed, and sometimes that perception of clear-headedness can make it seem like driving is an actual possibility.

I’ll go so far as to say that you shouldn’t drive until the next day after taking acid, because while a trip usually lasts only 8 hours, you will not be 100% sober until getting to sleep.

Take more acid

Classical psychedelics (LSD and magic mushrooms) build tolerance fast. Unimaginably fast, in fact. Tolerance builds from within the space of approximately 30 minutes to 2 hours. Redosing acid after this time often has little to no effect. Redosing will not bring about a second peak and for many it will not increase visuals or headspace by a great deal. Anecdotally, I have read that all it does is increase the (already long) duration of a trip.

Smoke weed

This is a controversial one. Many consider weed and psychedelics to be a match made in heaven. I have come across numerous people who say they never trip without some cannabis to smoke alongside. The thing is, I see where they are coming from because weed can seriously alter the way a trip feels.

But this is the exact reason why newcomers may want to abstain from smoking. LSD is a complicated drug and weed does nothing but make it more complex. A psychedelic experience can never truly be predictable but yet somehow weed makes a trip even less predictable. Weed brings its own properties and if you’re not experienced with both drugs then it can be hard to get a grip of what is happening when they combine.

This is why weed is often the culprit when it comes to bad and uncomfortable trips. It can make a small quantity of LSD feel like a lot, and a lot feel like too much. If you are to smoke on LSD then my advice is to keep it to a minimum, and take regular breaks because weed can take up to 15 minutes to take full effect sometimes.

For further critical discussions on the psychedelic experience, visit my website. I am currently crafting a magazine comprised of topics just like this one!

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